<script> function changeMapImage(imgPath) { document.getElementById('map1').src = imgPath; } </script>
レスポンシブとかで複数ある場合
<script> function changeMapImage(imgPath) { document.getElementById('map1').src = imgPath; document.getElementById('map2').src = imgPath; } </script>
<section class="map"> <img id="map" src="001.png" border="0" width="600" height="600" usemap="#map"> <map name="map"> <area shape="rect" coords="212,35,388,125" href="contents/" onmouseover="changeMapImage('101.png')" onmouseout="changeMapImage('000.png')"> <area shape="rect" coords="12,241,119,362" href="event/" onmouseover="changeMapImage('102.png')" onmouseout="changeMapImage('000.png')"> </map> </section>